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Effective, natural approaches may be a better choice
A combination of three important nutrients, arginine, magnesium and pyruvate, has helped support many migraine sufferers. Take 2 tsp. each of L-arginine, magnesium citrate, and pyruvate, dissolved in a full glass of warm water, along with 400 mg of ibuprofen, followed by a high protein snack. Read below for the science behind this emergency formula.
May be repeated in 6 hours if needed.
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There is a direct relationship between migraine and low dietary folate intake. Folate is NOT folic acid! We recommend:
L Methylfolate if you suspect you have an MTHFR variant.
Natural B-Complex For Everyone.
The Science
Folate: There is a direct relationship between migraine and low dietary folate intake. Folate is NOT folic acid! more than 1/2 of the general population carries at least 1 copy of a gene (MTHFR) that blocks your body from using the chemistry set inspired folic acid. Targeting MTHFR for the treatment of migraines. Expert Opin Ther. https://doi.org/10.1080/14728222.2019.1549544
Riboflavin (B2), Coenzyme Q10, Feverfew, Magnesium, Melatonin, Butterbur
Nutraceuticals and Headache 2024: Riboflavin, Coenzyme Q10, Feverfew, Magnesium, Melatonin, and Butterbur. Curr Pain Headache Rep. https://doi.org/10.1007/s11916-025-01358-3
Emergency Formula Explanation
Arginine is a chemical precursor to nitric oxide (a vasodilator). Early evidence suggests that arginine may help treat medical conditions that improve with increased vasodilation, including vascular headaches, erectile dysfunction, chest pain, atherosclerosis, heart disease or failure, and intermittent claudication/peripheral vascular disease. (Mayo Clinic) L-arginine and aged garlic extract for the prevention of migraine: a study protocol for a randomised, double-blind, placebo-controlled, phase-II trial (LARGE trial). BMC Neurol. https://doi.org/10.1186/s12883-023-03149-y
Magnesium has a strong vascular dilating effect, and cerebral blood vessel cells are particularly sensitive to it. The American Academy of Neurology supports use of magnesium in treating migraines. Preventive Migraine Treatment. Continuum (Minneap Minn). https://doi.org/10.1212/con.0000000000000199
Pyruvic Acid (pyruvate) is a by-product of glucose metabolism (glycolysis). It is used by the body for mitochondrial energy production. Low cellular energy has been linked to the start of migraines.
Traditional Chinese Medicine has been used to treat migraine attacks for millenia. In TCM, migraines are typically seen as a result of an imbalance or disharmony in the body’s Qi (energy), Blood, and organ systems—particularly the Liver, Spleen, and Kidneys. Specific symptom patterns are considered in choosing individual herbal formulations. Most commonly, a formula that invigorates qi and blood circulation and removes qi and blood stagnation is appropriate.
Triptans (Imitrex, Zomig, Maxalt) are serotonin receptor agonists that help constrict blood vessels and block pain pathways in the brain. CGRP Inhibitors (e.g., Aimovig, Ajovy, Emgality, Vyepti, Nurtec, Ubrelvy) block the action of a calcitonin gene-related peptide.
Both classes of drugs are somewhat more effective than aspirin plus caffeine. Unlike aspirin and other natural treatments, they have a host of adverse side effects and should not be used by those with heart disease, uncontrolled high blood pressure or stroke history, or those on an antidepressant (triptans).
There are three major categories of headaches
- Primary headaches: These include migraine, tension, and cluster headaches, as well as a variety of other less common types of headache. These are by far the most common types of headaches.
- Cranial neuralgias, facial pain, and other headaches: These headaches are related to inflammation of the nerves. Often there is a sharp, shooting pain that is momentary but characteristically recurs. It may be precipitated by touch to a sensitive area or may occur spontaneously. Neuralgias may follow nerve trauma, herpes zoster infections, or may arise spontaneously.
- Secondary headaches: Headaches that are caused by some other condition, such as hypertension or by conditions that affect the brain and its coverings. Infections of the head and neck may have headache as a symptom. Head trauma, even if it is mild, can often lead to headache. Anything that takes up space inside the head can cause headache, including tumor, subdural hematoma and hydrocephalus.
If you experience a very severe headache that you suspect is a secondary headache or cranial neuralgia you should seek medical attention immediately.
If you experience severe or recurrent headaches it is important to look for causes and triggers. Treatable causes of headache include bacterial and viral infections, nutritional deficiencies, allergies and food intolerances, high blood pressure, high or low blood sugar and reactions to many medications.
Traditional Chinese Medicine practitioners differentiate groups of symptoms into a specific pattern, and then treat that pattern as it manifests in each individual patient:
Wind Cold Pattern symptoms include: sporadic pain, stiff, aching shoulders; an aversion to cold temperatures; aggravation of the condition by wind; absence of thirst; a thin-white tongue coating; and a floating-tight pulse.
Wind Heat Pattern symptoms include: a painfully-swollen sensation in the head; severe, “splitting” pain; fever, or an aversion to warm temperatures; red face; red eyes; thirst; constipation; dark-colored urine; a red tongue body with a yellow tongue coating; and a floating-rapid pulse.
Wind Dampness Pattern symptoms include: heavy-feeling pain; a “muzzy,” or confused feeling; a feeling of heaviness in the whole body; chest congestion; aggravation of symptoms by damp weather; difficult urination; loose bowels; a sticky-white tongue coating; and a soggy pulse.
Liver Yang Pattern symptoms include emotional disturbance (especially feelings of anger); pain with dizziness; anxiety; anger; insomnia; hypochondriac (under the ribcage) pain; red face; a bitter taste in the mouth; a thin-yellow tongue coating; and a wiry-strong pulse.
Kidney Deficiency Pattern symptoms include general weakness; low-level pain with a feeling of “emptiness”; dizziness; sore back; fatigue; spontaneous seminal emissions (in men), or abnormal vaginal discharge (for women); ringing in the ears; sleeplessness; red tongue; and a thin-weak pulse.
Blood Deficiency Pattern symptoms include chronic illness; pain with dizziness; heart palpitations; fatigue; pale complexion; a pale tongue body with a thin-white tongue coating; and a thin-weak pulse.
Blood Stagnation Pattern symptoms include: chronic pain; pain in a fixed location; sharp pain, such as pain from a head injury; a purple tongue body with a thin-white tongue coating; and a thin or thin-choppy pulse.
Phlegm Retention Pattern symptoms include chronic over-weight and cravings for sweet and fatty foods; dull head pain with a feeling of heaviness and/or muzziness; a sensation of fullness and oppression of the chest; a feeling of nausea and phlegm retention in the throat; a white-sticky tongue coating; and a slippery or wiry-slippery pulse.
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Statements contained herein have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat and cure or prevent disease. Information provided by CHS is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. Any information given is only intended as a sharing of knowledge and information from scientific world literature. You are encouraged to make your own health care decisions based upon your own research of the subject and in partnership with a qualified health care professional.